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31 August 2020 : Database Analysis  

CDK1, CCNB1, and CCNB2 are Prognostic Biomarkers and Correlated with Immune Infiltration in Hepatocellular Carcinoma

Yiping Zou12CE, Shiye Ruan1CD, Liang Jin1C, Zhihong Chen1BF, Hongwei Han1DF, Yuanpeng Zhang1F, Zhixiang Jian1G, Ye Lin1D, Ning Shi1AE, Haosheng Jin1AG*

DOI: 10.12659/MSM.925289

Med Sci Monit 2020; 26:e925289

Figure 7 (A–C) CDK1, CCNB1, and CCNB2 expression levels were significantly related to tumor purity and significant positive correlations existed with immune infiltration cells including CD4+ T cells, CD8+ T cells, B cells, neutrophils, macrophages, and DCs in HCC. (D) CNA of CDK1 had significant correlations with immune infiltration cells including CD4+ T cells and B cells. CNA of CCNB1 had significant correlations with CD4+ T cells, neutrophils, and macrophages. CNA of CCNB2 had a significant correlation with CD4+ T cell. CNA, copy number alteration.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750