01 October 2020 : Database Analysis
COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis
Liuxun Li1ABCDEF, Meiling Yang2BCDEF, Anmin Jin1ABCDEFG*DOI: 10.12659/MSM.925474
Med Sci Monit 2020; 26:e925474
Figure 6 Detection of hub genes. (A) A Venn diagram presenting hub genes under coexpression and those involved in the PPI network. (B) Ten hub genes (COL3A1, POSTN, COL6A3, COL14A1, SERPINH1, ASPN, OGN, THY1, NID2, and TNMD) overlapped between the PPI and the coexpression networks. In the heat map, intensity and color of hub genes are shown at right, which represent the gene rank 1 to 10. PPI, protein-protein interaction; COL3A1 – collagen type III alpha 1 chain; POSTN – periostin; COL6A3 – collagen type VI alpha 3 chain; COL14A1 – collagen type XIV alpha 1 chain; SERPINH1 – serpin family H member 1; ASPN – asporin; OGN – osteoglycin; THY1 – Thy-1 cell surface antigen; NID2 – nidogen 2; TNMD – tenomodulin.