23 June 2020 : Laboratory Research
A PD-L1 Aptamer Selected by Loss-Gain Cell-SELEX Conjugated with Paclitaxel for Treating Triple-Negative Breast Cancer
Xiaoqiu Wu123BEF, Fangfei Li123AG, Yongshu Li1BF, Yuanyuan Yu13DF, Chao Liang13C, Baoting Zhang4DE, Chuanzong Zhao56B, Aiping Lu12378AG, Ge Zhang123AG*DOI: 10.12659/MSM.925583
Med Sci Monit 2020; 26:e925583
Figure 3 Aptamer selection. (A) Binding ability of enriched ssDNA library and unselected library to target cells. (B) Binding ability of enriched ssDNA library and unselected library to PD-L1 protein. The concentration of ssDNA pool was 250 nM. The data are presented as mean±standard error of the mean and were analyzed by Student’s t-test.