Figure 4 CCNG2 decreases the capacity of HTR8/SVneo cells to integrate into HUVECs. (A, C) Fluorescent images showing the 24-h co-culture of HUVECs with HTR8/SVneo cells overexpressing CCNG2 (A) and HTR8/SVneo cells with CCNG2 silencing (C). The left images show the cellular networks formed by green-stained HTR8/SVneo cells. The middle images show the cellular networks formed by red-stained HUVECs. The right images show the merged images. Original magnification×100. (B, D) Statistical analyses of the integration into HUVECs of HTR8/SVneo cells overexpressing CCNG2 (B) and HTR8/SVneo cells with CCNG2 silencing (D), as determined using ImageJ software. Each experiment was independently performed 3 times.* P<0.05 and ** P<0.01 vs. control.