Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer

Dawei Ning; Kai Cui; Min Liu; Yang Ou; Zhendan Wang; Benkui Zou; Yangyang Shen; Xinyang Lu; Sheng Li; Pang Li

doi:10.12659/MSM.926565

07 January 2021 : Clinical Research

Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer

Dawei Ning^1BCEF, Kai Cui^2BC, Min Liu^2D, Yang Ou^3BCEF, Zhendan Wang^4B, Benkui Zou^5B, Yangyang Shen^6B, Xinyang Lu^7B, Sheng Li^8AG*, Pang Li^9AB

DOI: 10.12659/MSM.926565

Med Sci Monit 2021; 27:e926565

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Figure 2 Circulating tumor cells (CTC)/circulating tumor microemboli (CTM) detected with the CTC-Biopsy system in patients with gastric cancer. Wright-Giemsa staining was performed for cytomorphological analysis. (A) CTC: nuclear-cytoplasmic ratio >0.8, irregular nuclear shape. (B) CTC: cell diameter >15 μm; abnormally large nucleoli. (C) CTC: thickened and wrinkled, with jagged nuclear membranes and side-shifted chromatin. (D) CTM: aggregation of tumor cells (≥3). All cells were analyzed under 40× magnification. Scale bar: 20 μm.

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Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer

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