24 November 2020 : Animal Research
Ethanol Extract of Chinese Hawthorn (Crataegus pinnatifida) Fruit Reduces Inflammation and Oxidative Stress in Rats with Doxorubicin-Induced Chronic Heart Failure
Fangzhou Cheng1AE, Wenlong Jiang2AB, Xiaoshuan Xiong2CD, Juan Chen2BC, Yunzhi Xiong2CF, Yinghong Li3FG*DOI: 10.12659/MSM.926654
Med Sci Monit 2020; 26:e926654

Figure 4 The effects of HAE on serum copeptin (A), adrenomedullin (B) levels, and histopathological changes in heart tissues (C) of rats in doxorubicin-induced CHF. Heart tissues were examined by hematoxylin and eosin staining using light microscopy (×100). Scale bar=100 μm. Results are expressed as the means±SD (n=8). # P<0.01 versus the control group; * P<0.05 and ** P<0.01 versus the CHF group. CHF – chronic heart failure; HAE – alcohol extract of hawthorn (Crataegus pinnatifida) fruit.