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24 November 2020: Animal Study

Ethanol Extract of Chinese Hawthorn () Fruit Reduces Inflammation and Oxidative Stress in Rats with Doxorubicin-Induced Chronic Heart Failure

Fangzhou Cheng 1AE* , Wenlong Jiang 1AB , Xiaoshuan Xiong 1CD , Juan Chen 1BC , Yunzhi Xiong 1CF , Yinghong Li 2FG*

DOI: 10.12659/MSM.926654

Med Sci Monit 2020; 26:e926654

Figure 4 The effects of HAE on serum copeptin (A), adrenomedullin (B) levels, and histopathological changes in heart tissues (C) of rats in doxorubicin-induced CHF. Heart tissues were examined by hematoxylin and eosin staining using light microscopy (×100). Scale bar=100 μm. Results are expressed as the means±SD (n=8). # P<0.01 versus the control group; * P<0.05 and ** P<0.01 versus the CHF group. CHF – chronic heart failure; HAE – alcohol extract of hawthorn (Crataegus pinnatifida) fruit.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750