07 October 2020>: Clinical Research
Overexpression of Facilitates Tumor Development and Is Correlated with Poor Prognosis in Clear Cell Renal Cell Carcinoma
Peng Chen 1BCDEF* , Ziying Zhang 12BCDEF* , Xiang Chen 1ACDEG*DOI: 10.12659/MSM.926755
Med Sci Monit 2020; 26:e926755
Figure 10 A series of genes coexpressed with PKMYT1 are revealed based on multi-database mining methods. (A) RAID map concerning miRNA, lncRNA, RBP, and TF interacting with PKMYT1. (B) The top 20 genes positively correlated with PKMYT1 expression in ccRCC based on the cBioPortal. (C) Heatmap of the top 50 DEGs that positively are coexpressed with PKMYT1 in ccRCC from the TCGA. (D) Venn diagram of the 52 common genes positively coexpressed with PKMYT1 in ccRCC through overlapping the TCGA, cBioPortal and GEPIA database. Abbreviations: RAID – RNA InterActome Database; miRNA – microRNA; lncRNA – long noncoding RNA; RBP – RNA-binding protein; TF – transcription factor; ccRCC– clear cell renal cell carcinoma; TCGA – The Cancer Genome Atlas; GEPIA – Gene Expression Profiling Interactive Analysis.