Overexpression of PKMYT1 Facilitates Tumor Development and Is Correlated with Poor Prognosis in Clear Cell Renal Cell Carcinoma

Peng Chen; Ziying Zhang; Xiang Chen

doi:10.12659/MSM.926755

07 October 2020 : Clinical Research

Overexpression of PKMYT1 Facilitates Tumor Development and Is Correlated with Poor Prognosis in Clear Cell Renal Cell Carcinoma

Peng Chen^1BCDEF, Ziying Zhang^12BCDEF, Xiang Chen^1ACDEG*

DOI: 10.12659/MSM.926755

Med Sci Monit 2020; 26:e926755

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Figure 6 Overexpressed PKMYT1 exerts negative effects on ccRCC prognosis. Survival analysis reveals OS between high PKMYT1 and low PKMYT1 mRNA levels in (A) all ccRCC cases from the TCGA database, (B) male patients, (C) cases with age >60 years, (D) TNM stage II, (E) cases at histological grade 4, and (F) ccRCC that has relapsed. ccRCC – clear cell renal cell carcinoma; OS – overall survival; TCGA – The Cancer Genome Atlas; TNM, tumor, node, metastasis.

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Overexpression of PKMYT1 Facilitates Tumor Development and Is Correlated with Poor Prognosis in Clear Cell Renal Cell Carcinoma

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