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20 October 2020 : Laboratory Research  

Verteporfin Promotes the Apoptosis and Inhibits the Proliferation, Migration, and Invasion of Cervical Cancer Cells by Downregulating SULT2B1 Expression

Lijun Yin1BCDEF, Guilin Chen2AF*

DOI: 10.12659/MSM.926780

Med Sci Monit 2020; 26:e926780

Figure 4 Verteporfin (VP) suppressed the SULT2B1 expression in cervical cancer cells. (A) The mRNA expression of SULT2B1 in normal cervical cells and cervical cancer cells was detected by RT-qPCR analysis. * P<0.05 and *** P<0.001 vs. H8 group. (B) The protein expression of SULT2B1 in normal cervical cells and cervical cancer cells was detected by western blot analysis. ** P<0.01 and *** P<0.001 vs. H8 group. (C) The mRNA expression of SULT2B1 in HeLa cells treated with 5 μM VP was detected by RT-qPCR analysis. *** P<0.001 vs. Control group. (D) The protein expression of SULT2B1 in HeLa cells treated with 5 μM VP was detected by western blot analysis. ** P<0.01 vs. Control group.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750