Figure 2 Identification of a 6 differentially expressed genes (6-DEGs) signature for prognoses of patients with clear cell renal cell carcinoma (ccRCC). Kaplan-Meier (KM) survival analysis was performed to evaluate the association between overall survival (OS) and 6-DEGs signature in (A) the training series, (D) the validation series, (G) the entire cohort, and (J) patients with metastatic disease (M1 stage patients). Receiver operating characteristic (ROC) analysis of the sensitivity and specificity of the 6-DEGs signature in (B) the training series, (E) validation series, (H) the full patient cohort, and (K) M1 stage patients. Scatter plots of survival status concerning the 6-DEGs risk score in (C) the training series, (F) validation series, (I) the full patient cohort, and (L) M1 stage patients.