Measurement of Cyclin D2 (CCND2) Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma

Yu Qian; Jing-Wen Wang; Yu Fang; Xiao-Dong Yuan; Yu-Chen Fan; Shuai Gao; Kai Wang

doi:10.12659/MSM.927444

15 December 2020 : Clinical Research

Measurement of Cyclin D2 (CCND2) Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma

Yu Qian^1ABCDEF, Jing-Wen Wang^1BC, Yu Fang^1BCD, Xiao-Dong Yuan^1B, Yu-Chen Fan^12ADF, Shuai Gao^12CDFG, Kai Wang^12ADEG*

DOI: 10.12659/MSM.927444

Med Sci Monit 2020; 26:e927444

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Figure 1 Flowchart describing the participant selection process. HCC – hepatocellular carcinoma; LC – liver cirrhosis; CHB – chronic hepatitis B; HCs – healthy controls.

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Measurement of Cyclin D2 (CCND2) Gene Promoter Methylation in Plasma and Peripheral Blood Mononuclear Cells and Alpha-Fetoprotein Levels in Patients with Hepatitis B Virus-Associated Hepatocellular Carcinoma

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