Figure 3 GO and KEGG analysis of the differentially expressed genes. The 46 DEGs were enriched in glutamate secretion, positive regulation of synapse assembly, and T cell receptor signaling pathway. For the molecular function, the genes were included in the aspects of MHC class II receptor activity, high-affinity glutamate transmembrane transporter activity, and L-glutamate trans membrane transporter activity. KEGG pathway analysis indicated the dysregulated genes were only enriched in the glutamatergic synapse pathway.