04 January 2021 : Animal Research
Sinomenine Improves Embryo Survival by Regulating Th1/Th2 Balance in a Mouse Model of Recurrent Spontaneous Abortion
Jin Luo1ABCDEFG, Yaqin Wang1ABCDEFG, Qianrong Qi1CE, Yan Cheng1BD, Wangming Xu1A, Jing Yang1AG*DOI: 10.12659/MSM.927709
Med Sci Monit 2021; 27:e927709
Figure 2 Effect of SIN on IFN-γ and IL-4 location in placental tissues of RSA mice. (A) Immunohistochemical staining for the expression of IFN-γ (a–c) and IL- 4 (d–f) in the placenta of the control (a, d), RSA (b, e) and SIN-treated (c, f) mice. Magnification: 400×. (B) H-score for the immunohistochemical staining intensity of IFN-γ, IL-4, and IFN-γ/IL-4 ratio. Data are expressed as mean±S.E.M.* P<0.05, compared with the control group; # P<0.05, compared with the RSA group.