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01 February 2021 : Animal Research  

Functional Doxorubicin-Loaded Omega-3 Unsaturated Fatty Acids Nanoparticles in Reversing Hepatocellular Carcinoma Multidrug Resistance

Chunlei Wang12ABEFG, Xiaoyan Wei12BDF, Guoliang Shao12ACFG*

DOI: 10.12659/MSM.927727

Med Sci Monit 2021; 27:e927727

Figure 8 Protein expressions of drug efflux transporters, MRP, LRP, BCRP, Bcl-2, and PKC-α in tumor tissues. The protein expressions were detected using western blotting, and β-actin was used as the internal control. Compared with the model group, & P<0.05, && P<0.01; compared with the DOX group, # P<0.05, ## P<0.01; compared with the vector-nano group, * P<0.05, ** P<0.01. BCRP – breast cancer resistance protein; Bcl-2 – B-cell lymphoma 2; LRP – lung resistance protein; MRP – multidrug resistance protein; PKC-α – protein kinase C alpha.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750