Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway

Jisheng Wang; Binghao Bao; Junlong Feng; Qi Zhao; Hengheng Dai; Fanchao Meng; Sheng Deng; Bin Wang; Haisong Li

doi:10.12659/MSM.928232

16 February 2021 : Animal Research

Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway

Jisheng Wang^12ABDE, Binghao Bao^12ABE, Junlong Feng^12ABCE, Qi Zhao^12BCF, Hengheng Dai^12BDF, Fanchao Meng^12BF, Sheng Deng^12DF, Bin Wang^2AG*, Haisong Li^2AE

DOI: 10.12659/MSM.928232

Med Sci Monit 2021; 27:e928232

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Figure 4 (A) Blood glucose of mice from groups A (control) and B (diabetic). (C, E) Sperm counts and total sperm viability in the 2 groups. (B, D, F) Scatter plot of blood glucose, sperm count and total sperm viability in the 2 groups of mice. Values are the mean±SEM (n=6 animals per group). The t test was used to compare group B with group A, * P<0.05.

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Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway

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