16 February 2021>: Animal Study
Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway
Jisheng Wang 12ABDE* , Binghao Bao 12ABE* , Junlong Feng 12ABCE* , Qi Zhao 12BCF* , Hengheng Dai 12BDF , Fanchao Meng 12BF , Sheng Deng 12DF , Bin Wang 2AG* , Haisong Li 2AE*DOI: 10.12659/MSM.928232
Med Sci Monit 2021; 27:e928232
Figure 6 (A) Western blotting showing expression of PI3K, p-Akt, p-FoxO1, FasL, p-Stat3, and IL-6 proteins. β-actin is a loading control. Scatter plot of western blot expression of (B) PI3K, (C) p-Akt, (D) p-FoxO1, (E) FasL, (F) p-Stat3, and (G) IL-6 protein in the 2 groups of mice: group A (control) and group B (diabetic). (H) The light blue bar chart represents expression of PI3K, p-Akt, p-FoxO1, FasL, p-Stat3, and IL-6 in group A. The deep blue bar chart represents expression of PI3K, p-Akt, p-FoxO1, FasL, p-Stat3, and IL-6 in group B. Values are the mean±SEM (n=6 animals per group). The t test was used to compare group B with group A. * P<0.05, ** P<0.01.