Effects of Pretreatment with Bifidobacterium bifidum Using 16S Ribosomal RNA Gene Sequencing in a Mouse Model of Acute Colitis Induced by Dextran Sulfate Sodium

Yi-jie Weng; Dan-xian Jiang; Jian Liang; Shi-cai Ye; Wen-kai Tan; Cai-yuan Yu; Yu Zhou

doi:10.12659/MSM.928478

09 March 2021 : Animal Research

Effects of Pretreatment with Bifidobacterium bifidum Using 16S Ribosomal RNA Gene Sequencing in a Mouse Model of Acute Colitis Induced by Dextran Sulfate Sodium

Yi-jie Weng^1BCDEF, Dan-xian Jiang^2BCDEF, Jian Liang^1BCDF, Shi-cai Ye^1BCD, Wen-kai Tan^1BCF, Cai-yuan Yu^1BCF, Yu Zhou^1ACDEG*

DOI: 10.12659/MSM.928478

Med Sci Monit 2021; 27:e928478

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Figure 1 Experimental design for this study. (A) Mice were treated with saline or Bifidobacterium bifidum ATCC 29521 from days 0 to 14 (2 weeks) and received dextran sulfate sodium (DSS) from days 0 to 7 in the treated groups. (B) Mice were treated with saline or B. bifidum ATCC 29521 from days 21 to 35 (5 weeks) and received DSS from days 0 to 7 in the pretreated groups.

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Effects of Pretreatment with Bifidobacterium bifidum Using 16S Ribosomal RNA Gene Sequencing in a Mouse Model of Acute Colitis Induced by Dextran Sulfate Sodium

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