09 March 2021 : Animal Research
Effects of Pretreatment with Bifidobacterium bifidum Using 16S Ribosomal RNA Gene Sequencing in a Mouse Model of Acute Colitis Induced by Dextran Sulfate Sodium
Yi-jie Weng1BCDEF, Dan-xian Jiang2BCDEF, Jian Liang1BCDF, Shi-cai Ye1BCD, Wen-kai Tan1BCF, Cai-yuan Yu1BCF, Yu Zhou1ACDEG*DOI: 10.12659/MSM.928478
Med Sci Monit 2021; 27:e928478
Figure 2 Weight loss and clinical activity score (CAS) of mice in the treated and pretreated groups. (A) No significant difference in weight loss was observed between the treated SL and treated BB groups. (B) Significantly less weight loss was observed in the pretreated BB group from days 31 to 34. (C) CASs of the treated BB group were remarkably reduced compared with those of the treated TL group (P=0.001). (D) CASs of the pretreated BB group were significantly decreased compared with those of the pretreated TL group (P=0.000). * P<0.05.