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18 December 2020: Database Analysis

Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study

Sha Qi ABC , Qiong Han BC , Danmou Xing D , Long Qian CE , Xiang Yu E , Dong Ren F , Huan Wang E , Quan Chen ABFG*

DOI: 10.12659/MSM.928788

Med Sci Monit 2020; 26:e928788

Figure 2 (A) Enrichment analysis results of upregulated genes: hsa00600, sphingolipid metabolism pathway; hsa04915, estrogen signaling pathway; hsa04512, ECM-receptor interaction pathway; hsa04010, MAPK signaling pathway; hsa04151, PI3K-Akt signaling pathway. (B) Enrichment analysis results of downregulated genes: hsa04390, Hippo signaling pathway; hsa04350, TGF-β signaling pathway; hsa03015, mRNA surveillance pathway; hsa04152, AMPK signaling pathway; hsa04360, Axon guidance pathway. ECM, extracellular matrix; MAPK, mitogen-activated protein kinase; PI3K-Akt, phosphatidylinositol-3-kinase and protein kinase B; TGF-β, transforming growth factor β.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750