18 December 2020: Database Analysis
Functional Analysis of Estrogen Receptor 1 in Diabetic Wound Healing: A Knockdown Cell-Based and Bioinformatic Study
Sha Qi ABC , Qiong Han BC , Danmou Xing D , Long Qian CE , Xiang Yu E , Dong Ren F , Huan Wang E , Quan Chen ABFG*DOI: 10.12659/MSM.928788
Med Sci Monit 2020; 26:e928788
Figure 8 ESR1 is enriched in patients with diabetic wounds (DWs) and regulates human skin fibroblasts (HSFs). (A) The expression of ESR1 in the 2 groups was measured by quantitative reverse-transcription polymerase chain reaction (qRT-PCR) analysis, n=30 per group. (B) The expression of ESR1 in cell groups with different treatments was measured by qRT-PCR analysis. (C) The CCK-8 results of HSFs in different groups. (D) The levels of cyclin D1 and cyclin D3 in different groups were measured by qRT-PCR analysis. (E) The levels of Bcl-2 and Bax were measured by qRT-PCR analysis.