Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression

Peng Li; Wenya Huang; Yi-ning Yan; Wenjing Cheng; Siyu Liu; Yang Huang; Wenjie Chen; Yi-ping Chen; Yuxun Gao; Weicheng Lu; Yijing Xu; Xianjun Meng

doi:10.12659/MSM.929027

27 May 2021 : Animal Research

Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression

Peng Li^1E, Wenya Huang^1E, Yi-ning Yan^2B, Wenjing Cheng^1C, Siyu Liu^3C, Yang Huang^1C, Wenjie Chen^1C, Yi-ping Chen^4D, Yuxun Gao^1D, Weicheng Lu^1B, Yijing Xu^1B, Xianjun Meng^1AG*

DOI: 10.12659/MSM.929027

Med Sci Monit 2021; 27:e929027

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Figure 3 Statistical graph of 5-hydroxytryptamine (5-HT) and dopamine (DA) content in rat serum and hippocampus samples. (A) 5-HT content in hippocampus. (B) 5-HT content in serum. (C) DA content in hippocampus. (D) DA content in serum. Compared with the control (Con) group, * P<0.05, ** P<0.01, *** P<0.001; compared with the chronic unpredictable mild stress (CUMS) group, # P<0.05, ## P<0.01, ### P<0.001. Data represent mean±standard error of the mean. AP – acupuncture; Fx – fluoxetine.

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Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression

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