27 May 2021 : Animal Research
Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression
Peng Li1E, Wenya Huang1E, Yi-ning Yan2B, Wenjing Cheng1C, Siyu Liu3C, Yang Huang1C, Wenjie Chen1C, Yi-ping Chen4D, Yuxun Gao1D, Weicheng Lu1B, Yijing Xu1B, Xianjun Meng1AG*DOI: 10.12659/MSM.929027
Med Sci Monit 2021; 27:e929027
Figure 7 Effect of acupuncture on the diversity and richness of intestinal flora in chronic unpredictable mild stress (CUMS) rats. (A) The Shannon index value indicates the diversity of samples. (B) Principal coordinates analysis (PCoA) for the distance between samples (β diversity) calculated using unweighted UniFrac distance. (C) A Venn diagram of the operational taxonomic units (OTUs) analyzes samples of different groups. (D) Relative abundance analysis at the phylum level. (E) Relative abundance of Firmicutes at the phylum level. (F) Relative abundance of Bacteroidetes at the phylum level. (G) Relative abundance of Bacteroidetes/Firmicutes at the phylum level. Compared with the control (Con) group, * P<0.05, ** P<0.01, *** P<0.001; compared with the CUMS group, # P<0.05, ## P<0.01, ### P<0.001. Data represent mean±standard error of the mean. AP – acupuncture; Fx – fluoxetine group.