19 April 2021 : Laboratory Research
Loss of Speckle-Type POZ Protein Promotes Prostate Cancer Cell Migration and Invasion Through Upregulation of MCP-1
Junlin Shi12ABCDEFG, Ji Cao3AG, Xiaomei Lu12B, Langlin Fan12B, Hongwei Guo12G, Jiejun Fu12ABCDEFG*DOI: 10.12659/MSM.929199
Med Sci Monit 2021; 27:e929199
Figure 2 The difference in soluble factors in the conditioned media of sgSPOP-1 cells, sgSPOP-2 cells, and control cells, as detected by chemokine antibody arrays and verified by ELISA and qRT-PCR. (A) The difference in expressed chemokines in the conditioned media of sgSPOP-1 cells, sgSPOP-2 cells, and control cells, as detected through chemokine antibody array. (B) ELISA was used to verify the MCP-1 expression level in the conditioned medium. The results are presented as the mean±SD of 3 independent experiments; ** P<0.01. (C) qRT-PCR measurement of the MCP-1 mRNA expression levels. The results are presented as the mean±SD of 3 independent experiments; * P<0.05, ** P<0.01.






