Combining Blood-Based Biomarkers to Predict Mortality of Sepsis at Arrival at the Emergency Department

Yinjing Xie; Binbin Li; Ying Lin; Fei Shi; Weibu Chen; Wenyuan Wu; Wenjia Zhang; Yun Fei; Shiqing Zou; Can Yao

doi:10.12659/MSM.929527

25 February 2021 : Database Analysis

Combining Blood-Based Biomarkers to Predict Mortality of Sepsis at Arrival at the Emergency Department

Yinjing Xie^1CE, Binbin Li^2BC, Ying Lin^1BD, Fei Shi^2AG*, Weibu Chen^1AF, Wenyuan Wu^1F, Wenjia Zhang^1B, Yun Fei^1D, Shiqing Zou^1D, Can Yao^2C

DOI: 10.12659/MSM.929527

Med Sci Monit 2021; 27:e929527

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Figure 2 The receiver operating characteristic (ROC) curves of the selected markers for predicting 28-day mortality of sepsis patients on arrival at the Emergency Department. The ROC curves for single markers and their combination included the following areas: high-sensitivity C-reactive protein (hs-CRP), 0.417; procalcitonin (PCT), 0.471; interleukin-6 (IL-6), 0.675; lactate, 0.710; white blood cell (WBC) count, 0.497; neutrophil-to-WBC ratio (NWR), 0.383; quick Sequential (sepsis-related) Organ Failure Assessment score (qSOFA), 0.512; combination of NWR, IL-6, PCT, and lactate, 0.823.

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Combining Blood-Based Biomarkers to Predict Mortality of Sepsis at Arrival at the Emergency Department

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