Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study

Min Jiang; Junwen Chen; Yuanhua Ding; Chenxi Gan; Ya Hou; Junge Lei; Mengzhi Wan; Xing Li; Zuke Xiao

doi:10.12659/MSM.929714

11 May 2021 : Clinical Research

Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study

Min Jiang^1ABDEF, Junwen Chen^2B, Yuanhua Ding^3B, Chenxi Gan^4BDF, Ya Hou^5CD, Junge Lei^1BE, Mengzhi Wan^1B, Xing Li^1B, Zuke Xiao^1ACG*

DOI: 10.12659/MSM.929714

Med Sci Monit 2021; 27:e929714

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Figure 1 Instructions for sea salt-derived physiological saline nasal spray use. The spray device consisted of a bottle (up to 60 mL), a hand pump, a nozzle, a dust cover, and sea salt-derived physiological saline. Instructions: (A) remove the dust cover; (B) tilt the head backward, put the nozzle in the nostrils, and gently press the manual pump 4 to 8 times per nostril (spray distance ≥200 mm); (C) wipe the nasal secretions and excess sea salt-derived physiological saline with a paper towel; (d) clean the nozzle and replace the dust cover.

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Efficacy and Safety of Sea Salt-Derived Physiological Saline Nasal Spray as Add-On Therapy in Patients with Acute Upper Respiratory Infection: A Multicenter Retrospective Cohort Study

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