Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

18 August 2021: Database Analysis

Genome-Wide Profiling of Alternative Splicing Signatures Associated with Prognosis and Immune Microenvironment of Hepatocellular Carcinoma

Zhikun Liu 12ABCDEF , Jiangwei Ye 13ABCDE , Abid Ali Khan 12ABCDEF , Jun Chen 12BCDE , Lin Zhou 2BCDE , Shusen Zheng 2ADE , Xiao Xu 12ADG*

DOI: 10.12659/MSM.930052

Med Sci Monit 2021; 27:e930052

Figure 9 Survival-associated SFs and splicing correlation network in HCC patients. (A) Splicing correlation network. AS events with PSI values negatively/positively associated with survival are shown in red/green dots, respectively. SFs related to survival are presented as purple dots. Green/red lines represent negative/positive between SFs expression and PSI values of AS, respectively. (B) High expression (red line) of splicing factor SRSF2 is strongly related to poor disease-free survival (left panel) and poor overall survival (right panel). (C) Dot plot of correlation between expression of SRSF2 and AP PSI values of CAPRIN1 (left panel), and the correlation between ES PSI values of SULT1A2 and expression of SRSF2 (right panel).

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750