20 August 2021 : Clinical Research
Association of Plasma Pro-Brain-Derived Neurotrophic Factor (proBDNF)/Mature Brain-Derived Neurotrophic Factor (mBDNF) Levels with BDNF Gene Val66Met Polymorphism in Alcohol Dependence
Min Mo1BCDEG, Xi-yue Fu2BCDF, Xu-lan Zhang1BD, Shao-chuan Zhang1BD, Hai-qing Zhang1CD, Li Wu1AF, Jia-lei Li1AF, Li Zhou1ACEFG*DOI: 10.12659/MSM.930421
Med Sci Monit 2021; 27:e930421
Figure 3 Correlations of plasma proBDNF and mBDNF levels with average daily ethanol consumption in the patients with alcohol dependence. Statistical analysis was performed with Spearman’s correlation test. (A) proBDNF (r=0.344, P=0.008) had a significant positive correlation with average daily ethanol consumption. (B) mBDNF (r=−0.361, P=0.005) had a significant negative correlation with total alcohol consumption. mBDNF – mature brain-derived neurotrophic factor; proBDNF – pro-brain-derived neurotrophic factor.