Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells

Xiaomeng Li; Yunpeng Zhang; Linglu Jia; Yixiao Xing; Bin Zhao; Lei Sui; Dayong Liu; Xin Xu

doi:10.12659/MSM.930610

07 June 2021 : Laboratory Research

Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells

Xiaomeng Li^12BFG, Yunpeng Zhang^13DEF, Linglu Jia^1BC, Yixiao Xing^1BC, Bin Zhao^1BC, Lei Sui^2CF, Dayong Liu^2EF, Xin Xu^1AD*

DOI: 10.12659/MSM.930610

Med Sci Monit 2021; 27:e930610

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Figure 6 Downregulation of PIP enhanced PDLSCs osteogenic differentiation. (A) ALP staining of PDLSCs after osteogenic induction for 14 days. (B) ALP activity assay of PDLSCs after osteogenic induction for 14 days. (C) Alizarin Red staining of PDLSCs after osteogenic induction for 21 days. (D) The protein level of ALP and COL1 in shNC and shPIP PDLSCs after 14 days of induction. (E) The quantitative analysis of western blot. * P<0.05.

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Downregulation of Prolactin-Induced Protein Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells

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