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19 August 2021: Lab/In Vitro Research

Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

Ben Wang 1ABEG , Shanjie Wang 2B , Wenke Wang 3BC , Enyu Liu 1BD , Sen Guo 1EF , Chuanzong Zhao 1CF , Jun Niu 1AD* , Zongli Zhang 1A*

DOI: 10.12659/MSM.930921

Med Sci Monit 2021; 27:e930921

Figure 1 Kaplan-Meier analysis of liver metastasis-free survival (LMFS) and overall survival (OS) for CRC patients with diabetes mellitus (DM group) and without diabetes mellitus (non-DM group). (A) LMFS curve of stage II patients (P<0.01). (B) LMFS curve of stage III patients (P<0.01). (C) OS curve of stage II patients (P<0.01). (D) OS curve of stage III patients (P<0.01). Significance of difference was evaluated by log-rank test.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750