Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

Ben Wang; Shanjie Wang; Wenke Wang; Enyu Liu; Sen Guo; Chuanzong Zhao; Jun Niu; Zongli Zhang

doi:10.12659/MSM.930921

19 August 2021 : Laboratory Research

Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

Ben Wang^1ABEG, Shanjie Wang^2B, Wenke Wang^3BC, Enyu Liu^1BD, Sen Guo^1EF, Chuanzong Zhao^1CF, Jun Niu^1AD, Zongli Zhang^1A*

DOI: 10.12659/MSM.930921

Med Sci Monit 2021; 27:e930921

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Figure 1 Kaplan-Meier analysis of liver metastasis-free survival (LMFS) and overall survival (OS) for CRC patients with diabetes mellitus (DM group) and without diabetes mellitus (non-DM group). (A) LMFS curve of stage II patients (P<0.01). (B) LMFS curve of stage III patients (P<0.01). (C) OS curve of stage II patients (P<0.01). (D) OS curve of stage III patients (P<0.01). Significance of difference was evaluated by log-rank test.

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Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

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