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19 August 2021: Lab/In Vitro Research

Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6

Ben Wang 1ABEG , Shanjie Wang 2B , Wenke Wang 3BC , Enyu Liu 1BD , Sen Guo 1EF , Chuanzong Zhao 1CF , Jun Niu 1AD* , Zongli Zhang 1A*

DOI: 10.12659/MSM.930921

Med Sci Monit 2021; 27:e930921

Figure 2 Immunohistochemical expression of αvβ6 in DM group and non-DM group. (A) Immunostaining of αvβ6 in representative colorectal cancer tissues of the DM group and non-DM group (×40). Bar=20 μm. (B) Box-and-whisker graph demonstrated that immunohistochemistry scores (IHS) of αvβ6 in the DM group were significantly higher than in the non-DM group. (C) Representative hematoxylin-eosin (HE) and immunohistochemical (IH) image of tissue microarray. * P<0.01 vs non-DM group.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750