19 August 2021: Lab/In Vitro Research
Hyperglycemia Promotes Liver Metastasis of Colorectal Cancer via Upregulation of Integrin αvβ6
Ben Wang 1ABEG , Shanjie Wang 2B , Wenke Wang 3BC , Enyu Liu 1BD , Sen Guo 1EF , Chuanzong Zhao 1CF , Jun Niu 1AD* , Zongli Zhang 1A*DOI: 10.12659/MSM.930921
Med Sci Monit 2021; 27:e930921
Figure 2 Immunohistochemical expression of αvβ6 in DM group and non-DM group. (A) Immunostaining of αvβ6 in representative colorectal cancer tissues of the DM group and non-DM group (×40). Bar=20 μm. (B) Box-and-whisker graph demonstrated that immunohistochemistry scores (IHS) of αvβ6 in the DM group were significantly higher than in the non-DM group. (C) Representative hematoxylin-eosin (HE) and immunohistochemical (IH) image of tissue microarray. * P<0.01 vs non-DM group.