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15 July 2021: Database Analysis

Epithelial Splicing Regulatory Protein 1 Is Overexpressed in Breast Cancer and Predicts Poor Prognosis for Breast Cancer Patients

Xinyu Liu 1ABCE , Qiangshan Wang 2B , Siqi Song 1B , Manman Feng 1B , Xiaoya Wang 1B , Ling Li 1B , Ying Liu 13B* , Chunying Shi 1BEG*

DOI: 10.12659/MSM.931102

Med Sci Monit 2021; 27:e931102

Figure 3 Analysis of ESRP1 expression in breast cancer cell lines and different molecular subtypes. (A) Analysis of mRNA expression level of ESRP1 in different types of cancer cell lines based on the Cancer Cell Line Encyclopedia (CCLE). (B) The mRNA expression level of ESRP1 in MCF-7 was higher than that in MCF-10A; * P<0.05. (C) The expression of ESRP1 in basal-like and Luminal A subtype were significantly higher than that of the Luminal B subtype of breast cancer, and the HR-sensitive subtype expressed higher level of ESRP1 than did triple-negative and Her-2 clinical subtypes (Gene Expression-Based Outcome for Breast Cancer Online, GOBO).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750