20 August 2021>: Animal Study
Knockout of the Cannabinoid Receptor 2 Gene Promotes Inflammation and Hepatic Stellate Cell Activation by Promoting A20/Nuclear Factor-κB (NF-κB) Expression in Mice with Carbon Tetrachloride-Induced Liver Fibrosis
Cuizhen Long 123ABCDEF* , Na Xie 12ABCDEF* , Yuanhui Shu 12ABCF , Yafeng Wu 14ABCF , Ping He 12BC , Yan Zhou 12BC , Yining Xiang 5CD , Junying Gu 12CD , Lei Yang 12DF , Yuping Wang 12ABCDEFG*DOI: 10.12659/MSM.931236
Med Sci Monit 2021; 27:e931236
Figure 2 HE staining of liver sections in 4 groups of mice. Deletion of cannabinoid receptor 2 (CB2) aggravated liver damage and inflammatory cell infiltration. (A) WT control group; (B) WT model group; (C) CB2−/− control group; (D) CB2−/− model group. HE, hematoxylin-eosin.