17 December 2021>: Animal Study
Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation
Cong Zhang 1ABF* , Cui-Lian Luo 1BCD* , Guan-Sheng Shang 1DE , De-Xiong Jiang 1BF , Qi Song 2AG*DOI: 10.12659/MSM.931630
Med Sci Monit 2021; 27:e931630
Figure 1 Effects of 5-fluorouracil (5-FU) and galangin on the proliferation of normal human esophageal cells and malignant cells. Het-1A, Eca109, and OE19 cells were incubated with different concentrations of 5-FU (A), galangin (B), and combined therapy (C) for 48–72 h, and the absorbance by CCK-8 assay was calculated compared with the control group independently. Data are shown as the mean±SEM of 3 independent experiments. * P<0.05 vs control group, ** P<0.01 vs control group for 48 h; # P<0.05 vs control group, ## P<0.01 vs control group for 72 h.