17 December 2021: Animal Study
Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation
Cong Zhang 1ABF* , Cui-Lian Luo 1BCD* , Guan-Sheng Shang 1DE , De-Xiong Jiang 1BF , Qi Song 2AG*DOI: 10.12659/MSM.931630
Med Sci Monit 2021; 27:e931630
Figure 4 Effects of fluorouracil (5-FU) and galangin on the apoptosis of human esophageal cancer cells. (A) Eca109 and (B) OE19 cells were treated with 5-FU, galangin, and combined therapy for 36 h and then analyzed with annexin V/propidium iodide double stain. (C) Quantitative analyses were conducted, and representative diagrams of flow cytometry analyses are displayed. Data are presented as the mean±SEM of 3 independent experiments. * P<0.05 vs control group; ** P<0.01 vs control group.