08 September 2021>: Animal Study
Pseudolaric Acid B Attenuates High Salt Intake-Induced Hypertensive Left Ventricular Remodeling by Modulating Monocyte/Macrophage PhenotypesFang-Fang Yu 1BE* , Guo-Hong Yang 1AG** , Shao-Bo Chen 1FG , Xiu-Long Niu 1F , Wei Cai 1CF , Yan-Yan Tao 1C , Xiu-Juan Wang 1BC , Ming Li 1BF , Yu-Ming Li 2DG , Ji-Hong Zhao 3AD*
Med Sci Monit 2021; 27:e932404
Figure 6 Flow cytometry analysis of mouse circulating monocyte subsets in different groups. (A) The gating strategy used for analysis of mouse circulating monocyte subsets. (B) The isotype control results of Ly6C-FiTC staining. (C) Representative temporal profiles of flow cytometry analysis (pseudocolor plots) in different groups. B shows the changes of Ly6Chi monocytes in different groups; D shows the changes of Ly6Chi monocytes in different groups; E shows the changes of Ly6Cint monocytes in different groups; and F shows the changes of Ly6Clo monocytes in different groups. Data are reported as mean±SD (n=10 per group). * P<0.05 vs LS group, # P<0.05 vs HS group, & P<0.05 vs HS+L-NAME group. HS – high salt; L-NAME – N-nitro-l-arginine methyl ester; LS – low salt; SSC – side-scattered light.