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08 September 2021 : Animal Research  

Pseudolaric Acid B Attenuates High Salt Intake-Induced Hypertensive Left Ventricular Remodeling by Modulating Monocyte/Macrophage Phenotypes

Fang-Fang Yu1BE, Guo-Hong Yang1AG*, Shao-Bo Chen1FG, Xiu-Long Niu1F, Wei Cai1CF, Yan-Yan Tao1C, Xiu-Juan Wang1BC, Ming Li1BF, Yu-Ming Li2DG, Ji-Hong Zhao3AD

DOI: 10.12659/MSM.932404

Med Sci Monit 2021; 27:e932404

Figure 6 Flow cytometry analysis of mouse circulating monocyte subsets in different groups. (A) The gating strategy used for analysis of mouse circulating monocyte subsets. (B) The isotype control results of Ly6C-FiTC staining. (C) Representative temporal profiles of flow cytometry analysis (pseudocolor plots) in different groups. B shows the changes of Ly6Chi monocytes in different groups; D shows the changes of Ly6Chi monocytes in different groups; E shows the changes of Ly6Cint monocytes in different groups; and F shows the changes of Ly6Clo monocytes in different groups. Data are reported as mean±SD (n=10 per group). * P<0.05 vs LS group, # P<0.05 vs HS group, & P<0.05 vs HS+L-NAME group. HS – high salt; L-NAME – N-nitro-l-arginine methyl ester; LS – low salt; SSC – side-scattered light.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750