08 September 2021 : Animal Research
Pseudolaric Acid B Attenuates High Salt Intake-Induced Hypertensive Left Ventricular Remodeling by Modulating Monocyte/Macrophage Phenotypes
Fang-Fang Yu1BE, Guo-Hong Yang1AG*, Shao-Bo Chen1FG, Xiu-Long Niu1F, Wei Cai1CF, Yan-Yan Tao1C, Xiu-Juan Wang1BC, Ming Li1BF, Yu-Ming Li2DG, Ji-Hong Zhao3ADDOI: 10.12659/MSM.932404
Med Sci Monit 2021; 27:e932404
Figure 9 Collagen deposition and cardiomyocyte hypertrophy in different groups. (A) Representative Masson-stained heart tissue images for collagen deposition. (B) Representative wheat germ agglutinin-stained heart section for cardiomyocyte hypertrophy. (C) Comparisons of collagen volume fraction. (D) Comparisons of cardiomyocyte cross-sectional area. Values displayed are mean±SD (n=5 per group). Scale bar indicates 100 μm. * P<0.05 vs LS group, # P<0.05 vs HS group, & P<0.05 vs HS+L-NAME group. CVF – collagen volume fraction; CSA – cross-sectional area; HS – high salt; L-NAME – N-nitro-l-arginine methyl ester; LS – low salt.