Figure 7 SNHG5 reverses the effect of high glucose induction. Angiogenesis (A, B) was analyzed in each group, and western blotting (C, D) was performed to analyze the changes in VEGF-A protein levels. Transfection of ov-SNHG5 or si-SNHG5 was divided into the control group, HG group, HG+ov-NC group, HG+ov-SNHG5 group, HG+si-NC group, and HG+si-SNHG5 group. * P<0.05; HG – high glucose; NC – negative control; VEGF – vascular endothelial growth factor; HRMECs – Human Retinal Microvascular Endothelial Cells. Photoshop software (version 21.2.4; Adobe, Inc; San Jose, USA) was used for creation of the figure.