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10 January 2022: Clinical Research

Expression of Long Non-Coding RNA (lncRNA) SNHG5 in Patients with Refractory Diabetic Macular Edema and Its Regulatory Mechanism

Junwen He 1ABEFG* , Zhang Rui 1BC , Jing Gao 2DE , Yanhong Chen 2DEF , Yanzi Li 1BCD , Tao Xu 1BDF , Shan Wang 2ABCE*

DOI: 10.12659/MSM.932996

Med Sci Monit 2022; 28:e932996

Figure 7 SNHG5 reverses the effect of high glucose induction. Angiogenesis (A, B) was analyzed in each group, and western blotting (C, D) was performed to analyze the changes in VEGF-A protein levels. Transfection of ov-SNHG5 or si-SNHG5 was divided into the control group, HG group, HG+ov-NC group, HG+ov-SNHG5 group, HG+si-NC group, and HG+si-SNHG5 group. * P<0.05; HG – high glucose; NC – negative control; VEGF – vascular endothelial growth factor; HRMECs – Human Retinal Microvascular Endothelial Cells. Photoshop software (version 21.2.4; Adobe, Inc; San Jose, USA) was used for creation of the figure.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750