Logo Medical Science Monitor

Call: +1.631.470.9640
Closed: National Holiday

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

10 October 2021 : Animal Research  

Pretreatment with Methylene Blue Protects Against Acute Seizure and Oxidative Stress in a Kainic Acid-Induced Status Epilepticus Model

Yong-feng Wang1E, Yan Luo2C, Gao-lei Hou1B, Rui-jing He3C, Hao-yun Zhang3F, Yan-Li Yi3D, Ying Zhang3B, Zhi-qiang Cui3AG*

DOI: 10.12659/MSM.933469

Med Sci Monit 2021; 27:e933469

Figure 1 Chemical structure and redox balance of methylene blue (MB). MB has powerful autoxidizable properties. It can accept electrons from an electron donor in its oxidized form and acts as an electron donor in its reduced form. At low concentrations in vivo, the 2 forms of MB are at equilibrium, forming a reversible reduction-oxidation system.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750