10 October 2021 : Animal Research
Pretreatment with Methylene Blue Protects Against Acute Seizure and Oxidative Stress in a Kainic Acid-Induced Status Epilepticus Model
Yong-feng Wang1E, Yan Luo2C, Gao-lei Hou1B, Rui-jing He3C, Hao-yun Zhang3F, Yan-Li Yi3D, Ying Zhang3B, Zhi-qiang Cui3AG*DOI: 10.12659/MSM.933469
Med Sci Monit 2021; 27:e933469
Figure 2 Schematic overview of the configuration of the guider cannula for kainic acid (KA) injection and electroencephalogram (EEG) recording. KA was injected into the right amygdala (anterior −0.94 mm, medial −2.85 mm, dorsal 4.75 mm) (indicated by the arrow) through a guider cannula (indicated by the vertical black line). For EEG recording, a single stainless-steel screw was implanted in the right frontal lobe to be used as a recording electrode. Two screws then were mounted over the left and right occipital lobes to act as an EEG reference and ground electrode, respectively. Two other screws were implanted to affix the dental cement.