Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

Zikuan Leng; Longyu Li; Xiang Zhou; Guangyao Dong; Songfeng Chen; Guowei Shang; Hongwei Kou; Bo Yang; Hongjian Liu

doi:10.12659/MSM.934660

14 February 2022 : Laboratory Research

Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

Zikuan Leng^1ACEFG*, Longyu Li^1BCF, Xiang Zhou^2BDF, Guangyao Dong^3BCE, Songfeng Chen^1DEF, Guowei Shang^1CDE, Hongwei Kou^1DF, Bo Yang^4ADF, Hongjian Liu^1AF

DOI: 10.12659/MSM.934660

Med Sci Monit 2022; 28:e934660

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Figure 2 Gene expression of mesenchymal stem cells related to cell proliferation and collagen secretion. The data in the columns with color were from the 10x single-cell RNA sequencing (scRNA-seq) according to the unique molecular identifier (UMI) counting formulated by log10 for standardization. The Smart-seq2 scRNA-seq analysis results quantifying the gene expression are shown as mean±standard deviation. The 10x scRNA-seq survey matched the Smart-seq2 scRNA-seq very well.

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Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

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