Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

Zikuan Leng; Longyu Li; Xiang Zhou; Guangyao Dong; Songfeng Chen; Guowei Shang; Hongwei Kou; Bo Yang; Hongjian Liu

doi:10.12659/MSM.934660

14 February 2022 : Laboratory Research

Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

Zikuan Leng^1ACEFG*, Longyu Li^1BCF, Xiang Zhou^2BDF, Guangyao Dong^3BCE, Songfeng Chen^1DEF, Guowei Shang^1CDE, Hongwei Kou^1DF, Bo Yang^4ADF, Hongjian Liu^1AF

DOI: 10.12659/MSM.934660

Med Sci Monit 2022; 28:e934660

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Figure 5 Monocle cell cluster analysis. (A) Three clusters were divided according to the differentially expressed genes (DEGs): Cluster 1 (▲), Cluster 2 (●), and Cluster 3 (◆). (B) The number of DEGs in each of the 3 clusters. (C) Gene heatmap of the top DEGs of the whole population based on the each top 10 DEGs unique to each cluster.

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Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing

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