16 April 2022: Database Analysis
Identification of Novel Genes and Associated Drugs in Cervical Cancer by Bioinformatics Methods
Dan Wang 1CDE , Yanling Liu 2F , Shuyu Cheng 1D , Guoyan Liu 123AG*DOI: 10.12659/MSM.934799
Med Sci Monit 2022; 28:e934799
Figure 7 Validation of the differential expression of 10 hub genes’ mutation rates and various clinical stages. (A) The cBioPortal database (http://www.cbioportal.org) shows that the 10 hub genes are known to be mutated in cervial cancer. (B) The mutation status of CDK1, AURKA, and PRC1 in cervial cancer is mainly shallow deletion, and the mutation status of AURKA and PRC1 is mainly amplification. (C) In the pathological staging of cervial cancer, the expression of CDK1, AURKA, and PRC1 were significantly differentiated in various clinical stages.