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19 May 2022: Animal Study

Anti-Inflammatory and Anti-Oxidative Effects of Isorhamnetin for Protection Against Lung Injury in a Rat Model of Heatstroke in a Dry-Heat Environment

Xiang Dong BDEF* , Jia-Jia Li BCDF* , Na Ma BC , Ai-Zhong Liu DF , Jiang-Wei Liu AEG*

DOI: 10.12659/MSM.935426

Med Sci Monit 2022; 28:e935426

Figure 3 Phospho-NF-κB and HMGB1 levels in the lungs of a heatstroke rat model pretreated with isorhamnetin. Levels of phospho-NF-κB (A, C) and HMGB1 (B, D) proteins, as detected by western blotting. Date represent the mean±SD, (n=5/group). ** P<0.01 compared with the NC group; # P<0.05 and ## P<0.01 compared with the HS group. NC – normal control; HS – heatstroke; L-AS – low-dose isorhamnetin; M-AS – medium-dose isorhamnetin; H-AS – high-dose isorhamnetin. VisionWorksLS 8.1.2 (UVP, LLC.) and SigmaPlot 12.5 (Systat Software, Inc.) were used for figure creation.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750