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10 May 2022: Lab/In Vitro Research

Impact of Factors Secreted by Tumor Cells on Response of Pleural Mesothelial Cells to Different Sclerosing Agents in an In Vitro Model

Michał Mierzejewski ABEF , Magdalena Paplińska-Goryca ABCDE* , Rafał Krenke ADEG

DOI: 10.12659/MSM.936065

Med Sci Monit 2022; 28:e936065

Figure 3 (A–C) TGF-β, MMP9, MCP-1 mRNA expression in mesothelial cells stimulated with sclerosants (doxycycline, PVP-I, talc, and TGF-β) cultivated with or without adenocarcinoma cell supernatant addition. Data are presented as median with interquartile range. DOXY – doxycycline; PVP-I – iodopovidone; TGF-β – transforming growth factor β; IL-6, IL-8 – interleukin 6 and 8; MMP9 – matrix metalloproteinase 9; MCP-1 – monocyte chemoattractant protein; RPMI – Roswell Park Memorial Institute medium. The figure was created using GraphPad Prism software (version 9.3.1). GraphPad Software, Inc., San Diego, CA, USA.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750