Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus

Adam Wróblewski; Justyna Strycharz; Katarzyna Oszajca; Piotr Czarny; Ewa Świderska; Tomasz Matyjas; Andrzej Zieleniak; Monika Rucińska; Lech Pomorski; Józef Drzewoski; Agnieszka Śliwińska; Janusz Szemraj

doi:10.12659/MSM.939299

09 July 2023: Clinical Research

Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus

Adam Wróblewski ^1ABCDEF** , Justyna Strycharz ^1ABCDEF* , Katarzyna Oszajca ^1CE , Piotr Czarny ^1E , Ewa Świderska ^1BEF , Tomasz Matyjas ^2EF , Andrzej Zieleniak ^3CE , Monika Rucińska ^2EF , Lech Pomorski ^2E , Józef Drzewoski ^4EG , Agnieszka Śliwińska ^5AEG , Janusz Szemraj ^1AEG

DOI: 10.12659/MSM.939299

Med Sci Monit 2023; 29:e939299

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Figure 5 The expression profiles of ATM, NFKB1, SOD2, INSR, and TIGAR among NGM (normal glucose metabolism), IFG (impaired fasting glucose), and T2DM (diabetic) female subjects. Statistics were based on −ΔDCt values and calculated with either one-way ANOVA with post hoc Tukey’s test or Kruskal-Wallis one-way ANOVA with post hoc Dunn’s test. Data are presented as dot plots with either mean±SD or median with interquartile range (ATM). Green dots, red squares, and blue triangles show results obtained for NGM, IFG, and T2DM females, respectively. (*) P≤0.05. The figure was generated using GraphPad Prism 6.0 (GraphPad Software Inc.).

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Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus

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