09 July 2023 : Clinical Research
Dysregulation of Inflammation, Oxidative Stress, and Glucose Metabolism-Related Genes and miRNAs in Visceral Adipose Tissue of Women with Type 2 Diabetes Mellitus
Adam Wróblewski
1ABCDEF*, Justyna Strycharz 1ABCDEF, Katarzyna Oszajca 1CE, Piotr Czarny 1E, Ewa Świderska 1BEF, Tomasz Matyjas2EF, Andrzej Zieleniak 3CE, Monika Rucińska2EF, Lech Pomorski 2E, Józef Drzewoski 4EG, Agnieszka Śliwińska 5AEG, Janusz Szemraj 1AEG
DOI: 10.12659/MSM.939299
Med Sci Monit 2023; 29:e939299
Figure 6 The expression profiles of 14 examined miRNAs among NGM (normal glucose metabolism), IFG (impaired fasting glucose), and T2DM (diabetic) subjects only. Statistics were based on −ΔCt values and calculated with either one-way ANOVA with post hoc Tukey’s test or Kruskal-Wallis one-way ANOVA with post hoc Dunn’s test. Data are presented as dot plots with either mean±SD or median with interquartile range (let-7g-5p, miR-20a-5p, miR-222-3p, miR-26b-5p, miR-374a-5p and miR-99b-5p). Green dots, red squares, and blue triangles show results obtained for NGM, IFG, and T2DM females, respectively. (*) P≤0.05. The figure was generated using GraphPad Prism 6.0 (GraphPad Software Inc.).