Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

Yosuke Sasaki; Takahiro Sato; Tadashi Maeda; Fumiya Komatsu; Naoyuki Kawagoe; Tsunehiko Imai; Tomoyuki Shigeta; Naoyasu Kashima; Yoshihisa Urita

doi:10.12659/MSM.940238

08 May 2023 : Clinical Research

Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

Yosuke Sasaki

^1ABCDEFG*, Takahiro Sato^1BDF, Tadashi Maeda

^1BDFG, Fumiya Komatsu

^1BCD, Naoyuki Kawagoe^1BC, Tsunehiko Imai

^1ACDF, Tomoyuki Shigeta

^1BF, Naoyasu Kashima

^1B, Yoshihisa Urita

^1ABDFG

DOI: 10.12659/MSM.940238

Med Sci Monit 2023; 29:e940238

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Figure 1 Propionate metabolism and measuring principle of the propionate breath test. Vitamin B12 functions as a coenzyme of methylmalonyl-CoA mutase in the conversion from L-methylmalonyl-CoA to succinyl-CoA in propionate metabolism. TCA – tricarboxylic acid.

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Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

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