Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

Yosuke Sasaki; Takahiro Sato; Tadashi Maeda; Fumiya Komatsu; Naoyuki Kawagoe; Tsunehiko Imai; Tomoyuki Shigeta; Naoyasu Kashima; Yoshihisa Urita

doi:10.12659/MSM.940238

08 May 2023: Clinical Research

Evaluation of the One-Hour C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B Deficiency

Yosuke Sasaki ^ABCDEFG* , Takahiro Sato ^BDF , Tadashi Maeda ^BDFG , Fumiya Komatsu ^BCD , Naoyuki Kawagoe ^BC , Tsunehiko Imai ^ACDF , Tomoyuki Shigeta ^BF , Naoyasu Kashima ^B , Yoshihisa Urita ^ABDFG

DOI: 10.12659/MSM.940238

Med Sci Monit 2023; 29:e940238

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Figure 3 Comparisons of RRs in 1-h PBT between macrocytic and normocytic patients. Horizontal axis and vertical axis indicate time (min) after 13C-propionate administration. and RR (%dose/h), respectively. Macrocytosis is defined as MCV >100 fL. The tinted area around each line indicates standard deviation. RR20 and RR30 were significantly low in VB12 deficiency group compared than in the normal group. MCV – mean corpuscular volume; PBT – 13C-propionate breath test; RR – 13C recovery rate; RR20 – RR at 20 min after administration of 13C-propionate; RR30 – RR at 30 min after administration of 13C-propionate; VB12 – vitamin B12.

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Evaluation of the One-Hour C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B Deficiency

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