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10 October 2023: Lab/In Vitro Research

Diagnostic Value of Synovial Fluid Biomarkers for Periprosthetic Joint Infection: A Prospective, Double-blind Trial

Ying Xu 123BCDE , Xueting Ma 4BCD , Haoran Guo 135CF , Hairong Tang 1BF , Jiayu Liu 1CD , Chengbin Wang 123AG* , Chi Wang 13ADF*

DOI: 10.12659/MSM.940842

Med Sci Monit 2023; 29:e940842

Figure 1 Synovial fluid S100A8, S100A9 and α-defensin were detected by MALDI-TOF-MS in PJI and non-PJI groups. PJI – periprosthetic joint infection; m/z=3374, HNP1; m/z=3345, HNP2; m/z=3489, HNP3; m/z=10833, S100A8; m/z=12688, des-MTCKM S100A9; m/z=13151, des-M S100A9; m/z=13273, S-nitrosylated S100A9; m/z=12249; IFS – internal reference standards. This figure was generated using QuanPRO protein quantitation mass spectrometer, Intelligene Biosystems (Qingdao) Co., Ltd., Beijing, China.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750