Figure 2 Kaplan-Meier curve analysis and hazard ratios (HRs) for recurrent acute coronary syndrome (ACS) in patients with ACS and a combination of diabetes mellitus (DM), or chronic kidney disease (CKD), or advanced age during the 3-year follow-up period. (A) Kaplan-Meier curve analysis for recurrent ACS between the ACS population with DM, CKD, or advanced age, or the combination of 2 or 3 risk factors (log-rank P<0.001). (B) In patients with 1 risk factor (DM, CKD, or advanced age), the HR of recurrent ACS was 1.13 (95% CI: 0.99–1.29; P=0.070), 1.63 (95% CI: 1.44–1.85; P<0.001), and 1.62 (95% CI: 1.38–1.91; P<0.001), respectively. In patients with a combination of 2 risk factors, the HR of recurrent ACS was 2.20 (95% CI: 1.81–2.67; P<0.001) for advanced age plus DM, 2.35 (95% CI: 2.08–2.66; P<0.001) for CKD plus advanced age, and 2.72 (95% CI: 2.45–3.03; P<0.001) for CKD plus DM. In elderly patients with DM and CKD, the HR of recurrent ACS was 2.99 (95% CI: 2.65–3.37; P<0.001) during the 3-year follow-up period.